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Extracellular vesicles: the new era of the intercellular communication

ROOM 5

 

WS.II

EXTRACELLULAR VESICLES:

The new era of the intercellular communication

 

September 21

 

Co-organized with:
Sapienza completa 400              Evita

WORKSHOP COMMITTEE:

Luciana DINI, Sapienza University of Rome
Stefano TACCONI, Sapienza University of Rome & NanoShare Srl
Annalisa RADEGHIERI, University of Brescia

Extracellular vesicles (EVs) have until recently been considered only cellular debris. Today they have been recognized as fundamental elements in intercellular communication.

They are a heterogeneous population of membrane-bounded vesicles that play important roles not only in cellular communication but also in preventing or promoting certain diseases, including infectious diseases, neurological disorders, metabolic alterations, and cancer. With this session, we want to highlight two fundamental aspects in the study of EVs: the techniques and innovative approaches for EVs isolation and characterization and give some examples of their role in the onset of diseases.

Considering the extreme heterogeneity of the EVs and the difficulty of establishing standard analytical procedures, in the first part of this session we will examine problems related to isolation, classification, and their characterization (morphological and biochemical). Furthermore, an example of isolation and use of EVs from milk will be provided as innovative possible carriers for the delivery of drugs or bioactive compounds.

The second part of the workshop will focus on the role of EVs in the development and progression of diseases, like cancer, metabolic diseases and in the physiological maintenance of the extracellular matrix.

The workshop will end with a symposium dedicated to young researchers in the field of extracellular vesicles.

For further information about abstract and poster template, please write to Prof. Luciana Dini, This email address is being protected from spambots. You need JavaScript enabled to view it. and Dr. Stefano Tacconi,  This email address is being protected from spambots. You need JavaScript enabled to view it.

 
 September 21
 09:00 - 10:30
Isolation and characterization of EVs
WS.II.1 - TT.I.B
Chairs: Luciana DINI, Sapienza University of Rome & Stefano TACCONI, Sapienza University of Rome & NanoShare Srl
WS.II.1.1
TT.I.B.1
Rienk NIEUWLAND - CV
Amsterdam UMC - University Medical Center, The Netherland
A roadmap to improve the reproducibility of extracellular vesicle research
NIEUWLAND Rienk
WS.II.1.2
TT.I.B.2
Simone DINARELLI - CV
CNR-ISM
High resolution atomic force microscopy as a tool for topographical mapping of surface budding
DINARELLI Simone
WS.II.1.3
TT.I.B.3
Piero DEL BOCCIO - CV
The ‘Gabriele d’Annunzio’ University, Chieti-Pescara
Proteomics characterization of FACS-sorted Extracellular Vesicles sub-types as liquid biopsy: new challenges in biomarkers discovery
DEL BOCCIO Piero
WS.II.1.4
TT.I.B.4
Stefano TACCONI - CV
Sapienza University of Rome & NanoShare Srl
Bovine milk-derived Extracellular Vesicles as new drug delivery system for bioactive compounds
TACCONI Stefano 2
 
 11:30 - 13:00
EVs in diseases

WS.II.2 - TT.II.B
Chairs: Anna Maria GIUDETTI, University of Salento & Stefania MESCHINI, ISS
WS.II.2.1
TT.II.B.1
Maria FIANI - CV
ISS
Metabolically labeled exosomes for biogenesis and functional studies
FIANI Maria
WS.II.2.2
TT.II.B.2
Anna Maria GIUDETTI - CV
University of Salento
Insulin-resistant M2-CD163+ macrophages release extracellular vesicles affecting lipid metabolism in muscle cells
GUIDETTI Anna Maria
WS.II.2.3
TT.II.B.3
Flora GUERRA - CV
University of Salento
Extracellular vesicle secretion promotes cisplatin chemoresistance in a context of late endocytic impairment
GUERRA Flora
WS.II.2.4
TT.II.B.4
Alberto DIASPRO - CV
University of Genoa
The era of the intelligent optical microscope towards extracellular vesicles visualization
DIASPRO Alberto
 
    14:00 - 15:30
PhD- derived EVs: implementing communication

WS.II.3 - TT.III.B
BROCHURE
Chairs: Annalisa RADEGHIERI, University of Brescia & Massimo BOTTINI, University of Rome Tor Vergata
WS.II.3.1
TT.III.B.1
Massimo BOTTINI - CV
University of Rome Tor Vergata
Matrix vesicles: biochemical, biophysical, and biological properties
BOTTINI Massimo 2022
WS.II.3.2
TT.III.B.2
Emanuela FRUSTACI
University of Rome Tor Vergata
Biophysical and biochemical characterization of matrix vesicles
!DONNA
WS.II.3.3
TT.III.B.3
Lucas NOGUEIRA
University of Rome Tor Vergata
Matrix vesicle-embedded biopolymeric scaffolds: a model for in vivo bone mineralization studies
!UOMO
TT.III.B.4
WS.II.3.4
Rossella ZENATELLI
University of Brescia
EV-protein corona and EV surface engineering, a first study
!DONNA
TT.III.B.5
WS.II.3.5
Diana VARDANYAN
University of Salento
A step toward precision medicine using extracellular vesicles derived from different temozolomide-treated glioblastoma cells
!DONNA
 

 

 
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